Monday, December 23

Touching Base Episode 6: Gene Therapy Restores Hearing and Innovative CAR T Manufacturing

Touching Base Episode 6 (January 26, 2024)

Summary:

  • An 11-year-old regains hearing after gene therapy.
  • Kyverna is using a blood draw instead of apheresis for CAR T manufacturing.
  • GSK and Elegen are using DNA production technology.
  • In StockWatch, Nvidia and Recursion are mentioned.
  • An interview with renowned cardiologist, Eric Topol, MD.

Restoring Hearing Loss

An 11-year-old boy who was born deaf was able to regain his hearing after undergoing gene therapy. The therapy involved injecting a modified virus that carried the correct version of the gene into the patient’s ear. The treatment successfully restored the boy’s hearing, allowing him to communicate with his family for the first time.

Kyverna’s Innovative CAR T Manufacturing

Kyverna, a company specializing in CAR T-cell therapy, has developed a new method for manufacturing CAR T cells. Instead of relying on apheresis, which requires the lengthy process of drawing blood, separating out the T cells, and then modifying them, Kyverna has created a technique that only requires a simple blood draw. This approach could streamline the CAR T manufacturing process, making it more efficient and accessible.

Advancements in DNA-Based Medicines

GSK and Elegen are collaborating on the development of DNA production technology. This technology aims to produce DNA-based medicines more efficiently and at a larger scale. By combining Elegen’s amplification technology with GSK’s capabilities and expertise, the collaboration hopes to accelerate the development of DNA-based therapeutics.

StockWatch: Nvidia and Recursion

In the StockWatch segment, the article briefly mentions Nvidia and Recursion. Further details about their involvement or any specific developments are not provided.

Interview with Eric Topol, MD

The article features an interview with Eric Topol, MD, a renowned cardiologist. Dr. Topol discusses the potential impact of technology and artificial intelligence on healthcare. He emphasizes the importance of utilizing technology and AI in patient care, diagnosis, and treatment, but also acknowledges the need for careful implementation and oversight to ensure patient safety and privacy.

Author’s Take:

The latest episode of “Touching Base” covers various advancements and innovations in healthcare and technology. From the heartwarming story of an 11-year-old regaining his hearing through gene therapy, to the cutting-edge techniques in CAR T-cell manufacturing, and the collaboration between GSK and Elegen for DNA production technology, the episode highlights the remarkable progress being made in these areas. The interview with Dr. Eric Topol emphasizes the significance of incorporating technology and AI in healthcare, while also cautioning about the importance of responsible implementation. Overall, the episode showcases the transformative potential of these technological advancements in improving patient outcomes and shaping the future of medicine.

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